the orange cab is alittle to middy... i could REALLY tell this the other day when i had my Mesa 4x12 with V30's and a friends orange 4x12 with V 30's.. I had my mk III on me at the time and we tired the mesa first, Huge tone.. big and powerful chunky chords and the tightness and clarity of the note was So SO nice.. then we tried the orange and it was like someone had striped all the gut's out and made it heap's middy..this also was the same for my own cab's when i had them a while back.. i really think this is why .. mk's are very mid based and for a cab to be very mid based things start to get bad..but amp's like the dual recto will sound a million bucks...the other guitarist in my band has this setup ...gibson LP custom SG-lead-dual recto-lead-orange.. That sounds huge..
for me MESA amp's are suited so well to mesa speaker's why bother changing thing's..