And put the delay in the the loop?
Having a delay in the loop and a delay in front will give you two different effects when using distortion. I imagine its similar for chorus, etc. Most people probably prefer these "time based effects" in the loop because its cleaner/studio sounding (and what most manufacturers suggest).
Its been a while since I used one, but a delay in the loop will be "clean". Your bends will sound "normal". But you can't do this "distorted delayed bend" thang (I can't describe it well). But if you heard/played it you would know what I'm talking about. Adam Jones does this as do many guitarist.
Essentially with the delay in front, your clean bend is being repeated into a distorted amp vs a distorted bend being repeated in a clean effects loop. The two produce different results when used with distortion, most noticeably with bends.
With a clean tone you're not going to notice much difference between effects in a loop or in front (unless its a parallel loop and blended with dry signal).
There may be some situations where you want both, a "clean sounding" studio-like loop delay, or a front delay for a specific effect.