No, Mesa didn't tune the Roadster cab to match the Roadster head. Having talked to Mesa about this, they made the Roadster cab to match the combo in size. This way, a combo owner could match up the Roadster combo on top of the 212 and create a 412 setup. After building it, the testers were very happy with how the Roadster ended up sounding through the cab. Having been told this, it makes me think that this must've come before the Stiletto cabs were built and designed, but alas that is speculation on my part. From what I was told by Mesa, the Roadster cab, while sounding good, was created out of necessity and aesthetic purposes. This would've been done with the Road Kings too, but the Road King 212s house two different speakers that require more space between one another, not to mention having a middle divider seperating the speakers completely. Again, this is all enlightening information that I received from a great conversation with Mesa when I was having some tube issues.
While the Orange is of similar dimensions as the Mesa, the Mesa does employ Vintage 30s that are very different than the Vintage 30s that most companies use. Whether or not Orange uses these same "old spec" Vintage 30s that Mesa uses is a mystery, but I was told that Mesa's Vintage 30s are different and of an older spec. Even though the Orange is similar, the sound is different than the Mesa Recto 212. The Orange has a pronounced midrange and highs -- lots of bass too, but that is to be expected with a cab of that size and design.
Talk to rezamatrix about this -- he uses the Orange now and loves it, but I believe he came from a Recto 212 and liked the change.
Good luck!