JBIRD: I'm not sure you know or understand how the Roadster works. If the knobs for the f/x are "off," then the user must depress the button marked "f/x" on the Roadster controller to engage the effects in the loop. Whatever channels are switched to f/x "on" will already have all engaged effects in the effects loop running automatically. The f/x on/off located for each channel on the Roadster allows the user to not tap dance, and just click on a channel and have the effects in the loop engaged. Do you understand? The Roadster is a bit complex, and if you don't have one or have never exercised this flexibility it can be confusing.
JBIRD: I noticed you were offended by my writing that you weren't coherent in your post. I am sorry I couldn't understand what you were writing, but it really wasn't coherent. You finished your statement with a question mark, even though it wasn't a question. Throwing stones at me and being defensive is a bit silly and unwarranted. You look sillier right now for typing in a large font "WHO'S COHERENT NOW." You haven't been coherent in either post and I can only hope you see how unruly you are being. Dude, seriously, why comment on an amp you don't have experience with? Or better yet, why call me out on something that you don't understand?
Getting back to what the poster's issues are -- clearly, if you checked the effects and your cords, then you've isolated the problem as coming from the amp itself. The next step is to figure out if it is a tube-based issue, send-level control issue, etc. There are a lot of things that can be happening. One of the best things you can do is call or contact Mesa. They are very helpful and can enlighten in ways you may not expect.