I would say Channel 2 Crunch or Channel 3 Mark IV mode. But since you're playing a Tele, most likely you'll find that Mark IV mode has the gain you'd want for this. The great thing about the Mark V is that with the graphic EQ you can really dial frequencies in or out, so you can really change the way your Tele sounds if you want it to be more like a Les Paul.
You wouldn't want to approach the V like you would any other amp (except for other Boogies). Let's take Channel 3 Mark IV mode as an example for now. You'd typically want the Bass control way low, like 3:00 or even lower if you need to, because turning it up will just make a flubby low end. The Treble control in this channel also adds gain as you turn it up and you'd typically want it quite high (well above halfway) to have a nice fluid lead sound. Mids you should adjust to taste and Gain should be fairly high up (like almost all the way up). One of the most important controls for me however in this mode is Presence - even a tiny little turn on this knob can totally change the high end sparkle content, so be careful with it.
You might want to use the graphic EQ too for a final tone shape and clarity. In this case, the first two sliders can go fairly high up, bringing in the bass you dialed out with the Bass control. The mid slider is the most powerful of all, you might find that you want to use it to scoop some mids out, because the V is a quite mid-heavy amp. The last 2 faders are your real Treble controls, adjust to taste. Leaving them in the middle or boosting them just a little might give you that Les Paul-ish tone even from a Tele.
These are just basic guidelines, I'm still figuring this amp out, too, but I absolutely love everything that comes out of it. Channel 2 Crunch can give you similar lower gain results while also being a little spongier. Also, I like to use the amp in full power 90 watts because I find it really has the most clarity that way. Channel 3 should also be set to Pentode in the back, Triode is smoother and not as ballsy
