It's very possible. I use the G-major for all my switching on my DR (3 channel), I use a Y cable (trs-dual mono) tip to channel 1 ring to channel 3 and channel 2 is default when the other 2 aren't selected. I never use solo and have fx always on and just have patches with nothing on them for dry sounds. You could use the 2 switches off the behringer to turn the solo on/off and f/x on/off if you want, or to switch channels on the amp if you don't want to use the g-major for it. And even though mesa and tc electronic both say it won't work, or not good for the amp or what not, the switching on the g-major has been working without a problem for a while now.