Yeah, all the solutions mentioned above will help. I find the sweet spot is below ear-shredding levels on my amp... loud, but not deafening.
I just played a gig at a jazz supper club where we had to control the levels significantly. All the tweaking and futzing I've been doing with 6V6s, the 5751 in V2, and getting happy with the Tweed setting amounted to one of the best-sounding shows I've had in a long time, and all I did was set up, turn on, and play. No complaints, no twiddling, nothing but comps on my tone. I was amazed. Really manageable, and no one got hurt.
Tweaks aside, one big adjustment I made recently was to rely on the Output knob for attenuation (as opposed to volume, if you will), so nowadays my channel Masters are around 11-12:00 and my Output and Solo are closer to 9:00 or 8:45, which still gives me some room to make small adjustments. I generally keep the Loop Send at 1:00-ish. And I've dropped the Presence controls to around 9:00 as well, which allows me to dial in some Treble and get some additional gain out of that; it brightens the tone without sounding brittle. At even slightly above apartment levels, the rig sounds really good to me.