I played my Mark V 25 through quite a few cabs all of which I own (except the Mesa Recto 1x12 which I got rid of).
Widebody Closed back 1x12 = Has a big sound a little loose in the lows and a little scooped in the mids but great for portability/size and weight.
Recto 2x12 = Full sounding but seems brighter then the Widebody 1x12.
Regular Recto 1x12 = If I didn't need to get super loud it was ok, very directional sounding.
Orange Jim Root 2x12 = Nice size, sounds darker then the Recto 2x12 and is lighter
Bogner 4x12 = One of the nicest 4x12 I have heard over the years, everything sounds great with it. Not Ideal for gigging for me because of Size and weight but fantastic in the studio.