i will give this a shot for you since no one else has, my lead sound is ch 3 100 w in the back, set to spongy, pres 2 bass all,mid 2, treb 230; gain 3 in the clock positions, master about 930 ,now all i use is ch 3 for lead and rhythm ,the big difference is i use a boss gt 8 for some delay and chorus connected in the 4 cable method ( you can get info on the boss gt forum how to do this) forget the tube screamer ect!!! when you solo just use the solo button on the mesa foot switch my clean is ch 2 set w/ volume matching ch 3 . i get a killer tone for dream theater ect ,some say perfect match!!! NOW YOU"LL HAVE TO READ UP ON STUFF BUT THATS THE BASIC IDEA!!! one important thing i forgot is ch 3 set to vintage and 2 clean , if you need some questions answered il try my best to help... cc PS ...the master amp volume will be all you need to adjust when you play out and get used to the solo function ,volume ect........and the gain on ch 3 shouldn't need to go past 3 o'clock.