I own both, a vintage 1966 Fender Super Reverb and a 1x12 Mesa LSC. My Mesa however is a small box head (10/50/100) and I opted for the ported 1x12 Roadster cabinet (same size as the 2x12 but with only one 12" V30 Celestion) for portability. The Fender Super Reverb is a heavy beast, but I'd think the 4x10 LSC would crush it in weight. My head alone is heavy and its a small box short style.
The other option, and it's realistic, is put some decent casters on the 4x10. The problem I have is getting a cabinet that big to fit easily into the front seat of my car. It'll do it, but it's tough to see out that side! The split version is simple. I can put the speaker in back easily and the head on the front seat, belted in. The 1x12 ported Roadster cabinet is the hugest sounding 12" Mesa cabinet I've played through, and smaller than any others that can still have a head sit on them. Much bigger sounding then the 2x12 Rectifier cabs with a better bass response, tighter IMO.
As far as getting that SRV/Texas tone from the LSC, it gets there in spades. I'd been playing my Super at local clubs for some time and the problem with them (besides the weight) is they have to be turned up pretty loud to get to the sweet spot, and you still need a Tube Screamer in front of that! Loud like around 6, but above 4 for sure. That's much too loud for any club I play in. My friend said it right about the LSC when I first brought it out. He said: "I know what your trying to get to with the Super Reverb, it's just that the LSC gets there so much sooner". He was spot on. In the clean channel the LSC really can dial in a fantastic Fender Blackface tone and get that grind much sooner then a real Fender can because of the drive channel. It also gets there without the harsh ice pick high end that many, many Fender amps (my Super included) seem to have. It's like the LSC is the Super Reverbs darker big brother. Meaner, tougher and brutal, but can be just as sweet when treated right. I bought the amp to get Andy Timmons tone, but found that it could become my general gigging amp and it gave me a LOT more versatility. Between channel two and one and my volume pot on the guitar, I can get just about anywhere with the LSC. With the Super Reverb, I can only go to Texas... with the LSC, I'm a world traveller!
One other thing I found on the LSC though is I seem to really only like it's tone when I have my EH Memory Toy delay in the loop. I don't know why, I'm not a big fan of delays per se, but without it the amp is kinda dry, even with the reverb engaged. I don't think Mesa's reverb is anywhere near the Super's and I like an amp to sound like it's big in a room, not dry. The Memory Toy in the effects loop really changes the character of the amp altogether in an absolutely beautiful musical way! It opens the amp up it seems. In fact, playing with the memory in the loop was a giant part of nailing the Andy Timmons' tone for me. I don't notice he uses a lot of delay, certainly not over the top by any means, just a subtle thing, and when he pointed it out on one of his Mesa gear videos where he talks about using two Memory Man echos together, he mentions that he leaves it on almost all the time. I had to really listen to hear the echos at all. But when he shut them off and just played with the reverb alone, suddenly it sounded like my amp! So, I was using the delay just inline on my effects board at the end of the chain and never used it because it just put notes in the way of each other and crapped everything up, I took it out and plugged it into the amps effects loop, and viola! I'd nailed his famous Lone Star tone.
I know your looking for the SRV tone, not Andy Timmons, but none-the-less the amp sounds lifeless and dull to my ears without the delay in the loop. Don't know why, but that delay in the loop really turned this amp into something I was considering selling into something I'd never part with. In fact I get nervous and all excited when I'm away from it just to get home and play it again to hear that sound. To me now, it's actually the amp that inspires me to play when none of my other amps were getting me there.
Hope this helps.