I'm DONE with 2 x 12 combos- just too heavy.
I have the 1 x 12 LSS combo with the 1x12 matching cab and it's perfect. IF I want cleaner, bigger, louder, I bring the 1 x 12 ext cab; otherwise, the 1 x 12 works fine, too.
Heads and cabs are the way to go. If I could do it over, I'd probably buy the LSS head with an Avatar 2 x 12 open back cab with the Celestion BLues. Get a LSC head, too and run it with the 2 x 12 cab. Then a Bogner head. Then a Bad Cat Head. Then a Dr Z head. On and on. Forever.
Then, a good 1 x 12 cab for when you don't want to bring the 2 x 12 out.
I take my Dr Z Maz 38 head out with the Boogie 1x 12 ext cab and its small, the weights are manageble, are the tone is great. Two trips, but less weight per trip.