I'm using a G&L SC2 with mine... I have my drive and gain set to about 1-2 o'clock my treble is at 1 o'clock my mids are about 12-1 o'clock and the bass is about 9-10 o'clock My presence is about 4 o'clock... Every guitar and player are different.. I just got mine a few weeks ago so far I like where all my settings are... I noticed this amp is very bassy...