I was on the phone with Mesa yesterday about something else and asked them about mixing tube types as long as they were rated at the same bias, and they advised against it without supplying any good reason. I told them there are plenty of people out there that run el34 bias setting with 2 el34s and 2 "hot" 6v6 tubes at same time, he sounded interested, but advised against it for no good reason, basically suggested I only use mesa tubes. I think he was just trying to supply me with a "safe" answer, because I really cant see what the difference would be as long as the tubes were rated to be at the fixed bias setting you are using....shouldnt make any difference at all!
Please correct me if im mistaken!
There are alot of people I have seen on here who mix it up as long as they are 2 matched sets, at the same relative rating between the 2 sets, and are paired outside to outisde, inside to inside.