My band is a 3-piece, and I'm the only guitar player, so by default I'm the solo guy. I have basically two solo sounds, a clean sound and an overdrive sound. For my clean solos I turn the guitar volume all the way up, turn the TBX tone control full on to 10, and use the second position on my strat. I use a dynacomp as a compressor and to boost the signal. amd engage a little delay as well.
For the overdiven solos, I'll shut off the compressor, and hit channel 2 on the amp and engage the graphic eq for boost (on my DC-3). Add delay and phase 90 to taste. Pretty basic set-up for me. Ideally I run a two amp stereo rig, and when I do I'll use either a little light stereo chorus or enjoy the stereo spread from mt delay pedal. Fills things out nicely in the 3-piece format.