George, something of a fuzz fan here... zvex fuzz factory, zvex machine, foxrox octron, skreddy mayo, skreddy ? lady, devi ever shoegazer are currently on my board.
I use them with the C+s as well as the IV. I will say that the IV is better suited as the C+s can get a bit bright. That said, dropping your presence down helps out dramatically.
What kind of fuzz are you looking for? Most of the above are not very musical. That's very subjective though. A lot of people mistakenly think you can get those massive walls of fuzz like smashing pumpkins or my bloody valentine out of a big muff alone and that just isn't the case. The biggest thing is that without proper low end from an actual bass player, fuzz is very harsh by itself. I've tracked tons of tracks with fuzz and it sounds awful without a bass player in the mix for the most part. There are definitely exceptions but it really depends a lot on the fuzz. High output pickups sound like junk with fuzz in my opinion.. something midrange output like LP 57 classics or burstbuckers for example are much better suited. Single coil pickups are also great with fuzz, believe it or not. When I say non musical, I just mean, you're not going to get gobs of sustain out of them, they are a bit finicky depending on the transistor type and your guitar.
The Foxrox Octron is probably the best/most musical pedal in that list above.. it actually DOES do all the things I just typed up that fuzz usually doesn't do. It has a nice midrange to it instead of just obscene bass and treble, it's very smooth, it's very easy to get good sustain and liquid lead tones with it...
I didn't mean to turn this into a fuzz tutorial but I just wanted to make sure you knew what you were getting into. You will fight and wrestle with your tone with a fuzz and get super frustrated but when you 'figure it out' it will fall into place nicely.
Another tip I have is turn your tone knob on your guitar way down or off and then use the pedal's tone control to shape.. it can get might ice picky and shrill in fuzz land.