The Mark V is the tube eater.... That is the amp I had the KT77 in use for a few months, not sure how long. This amp can burn up tubes in a matter of a few hours if they are weak. I have to proceed with caution though, since I had the KT77 in the Mark V when I blew out one of the screen resistors. A few things need to be checked out with that amp to confirm what is the issue. All I need to do is confirm the bias is at -51V when powered from the same AC source. Of course getting a bias meter would also help.
As for the RA100, I do not have any issues with it eating tubes. The KT77 failed or shut down due to soft short or contaminants. Nothing has red plated yet. I marked the suspect bad tubes and set them aside. I have tried them again in the RA100 and they are working fine. The HT fuse is still good and the LED was not lit either. Could be loose pins, not sure the issue. So it appears the quad of KT77 may still be okay for a little while. As for the old Mesa tubes, I cracked one by accident (dropped one of the tubes that hit and cracked the one on the carpet) and did not realize it until I turned the amp on. However, one of the sockets is loose, so perhaps pulling the amp out, remove the upper board to gain access to the power tube board for inspection of all solder joints may be in order if the issue becomes persistent. Issue does not arise with new tubes, so considering old tubes failing or shutting down if they are near end of life is no reason to take apart the RA100 to confirm amp or tube related (95% convinced it is tube related and 5% the amp since I bought it used).
As for the SED tubes, I have use them for nearly 6 months and always used the power soak which will wear tubes a bit faster especially when pushing the master volumes up. I have to consider that the preamp tubes I have been using in the RA100 have been use quite well back in the 90's when I was in a band. I wound up with a small stock pile of Mesa tubes that were either spent or still good. Some of them were given to the person I sold the Mark III. I held on to a few of them.
As for the Ruby EL34BHT, there are two that will glow a bit like a 6V6. It does not matter what amp I have them in, Roadster, RA100 or Mark V, just two of the tubes are not so great. That was kind of sucky actually. I should have returned the pair back to Doug's Tubes but considering how long it took to have an RMA on a Rectifier tube evaluated, I simply said to myself, "screw it".
Also have to consider I am on a tone quest. I am hoping to fine a quad of power tubes that are as pleasing as the SED =C= EL34. Since I am preparing to record various power tubes, I believe I will be able to include the KT77 (used up but still have some life left I hope), I will throw in the Ruby EL34BHT, even the Ruby 6L6GCMSTR, perhaps a Quad of Mesa STR440, I should have new Mesa EL34 in by mid week, SED =C= 6L6GC (put them in last night and Holly $h#t, they sound incredible in this amp), Tung Sol EL34B, Mullard EL34, and SED EL34. Possibly Tung Sol 7581. Basically I am going to run though my stash of power tubes if I have the time to do it.