I'm a troll on this subject but I think its a truly bad idea.
Want an amp that mixes power tubes types - buy one that does that or recognize you are taking a real risk with your amp.
The amp is not just tubes - other parts behave differently based on the tubes and the setting for the tubes, like the transformer! Doing something it wasn't designed to do is at best a risk even if it sounds good. Can you afford to possibly trash parts of your amp?
I like Bob in general but in this kind of advice he's gambling with other peoples stuff and voiding their warranty for them which as a business practice I cannot endorse. Look at what happened to the Peavey JSX amps that he recommded EL34-L tubes when the screens were not big enough to handle them.
Peavey's fault? I'm really not as sure as Bob is on his site about this. These were not the tubes the amp was designed for, period. They draw differently than regular EL34s. He's got a disclaimer up there now, which is great, but it still emphasizes that stuff like this is a risk which is my point.
Thats all I'm saying. Again, I'm not hating on Bob, just recognizing that he's a guy with amps plural and some of the guys here have one precious Mesa and I'd hate to see them possibly toast it and void their warranty too.
-P