To me cables are just a link in the chain. They won't make things better, but they can definitely make things worse. People get all caught up in the technical specs and such. I tend to focus on the physical durability first. Unless you're using 30 foot cables (and you shouldn't be - get a wireless unit) "most" cables will sound just fine. After all Hendrix used those cheap old coiled cables and people worship the tones he got. My take is: don't buy cheap junk and don't buy the most expensive hyped up crap either. I'm sorry but $50 for a 10 foot guitar cable is ridiculous. As long as it has good quality plugs, a durable jacket, plenty of shielding to cut out noise and interference, and decent capacitance specs, it will work just fine. If you're that worried about cable specs, get an impedance converter and run Lo-Z mic cables. Their signal specs are far better for long runs. Also, DO NOT use instrument cables between your amp and cab. They are not built to take those kinds of currents and will get very hot and even melt. Use good quality speaker cable of the largest practical diameter you can find. Plugs are extremely important on speaker cables too. If a plug or connection fails that means your high dollar tube amp has no load, and it will fry your output transformer. Not Good at all.