I just picked up a Nova System myself. Granted, I use a different amp than you, I've gotta say the sound quality is superb! I've been working on an ambient patch for volume swells that uses vibrato, reverb, delay, some distortion from the analog drive circuit, and an octave up from the pitch section for a hint of "shimmer" a la Edge. I'm still tweaking and perfecting, but even as is, it sounds stellar.
Sadly, since you have the MkV, it doesn't make much sense to run the Nova in front of your amp like I do, and the analog drive circuit is half the magic of the Nova. I don't know how your cash flow is, but maybe check eBay for used G-Systems. That would be a better fit for your amp, in my opinion.
Actually, let me rephrase that... If you plan on using the majority of your effects in Channel 1 set to a clean sound, then the Nova would be an excellent fit!