I'm not following your wiring scheme (getting confused, lol)... but I CAN tell you how the 2:100 works...
The 2:100 has TWO channels (each at 100 watts). Each channel has 3 output plugs... one, labeled 8ohm, and two others (which are "paired" together) labeled at 4ohm.
The 8ohm jack must see an 8ohm load. So... whatever wiring scheme you use, this jack must see an overall load of 8ohm connected to it.
(This could be a single 8ohm speaker; or two 4ohm speakers in series; or two 16ohm speakers in parallel; there are more possibilities with four speakers, but if I read your post right, I'm sure you are talking about pairs/sets of two speakers.) Also note: The 8ohm jack on the other channel work the same.
Now... for the "paired" 4ohm jacks. Whatever you plug into these jacks... the amp connects these jacks together in parallel
internally. So... if you take two 8ohm speakers, connect one into one of the 4ohm jacks, and the other into the other 4ohm jack... the amp will only see a 4ohm load, which is what it wants (cause two 8ohm loads in parallel is 4ohm). As far as I recall, you do not have to load each jack on the paired 4ohm outputs (or at least, I have not heard otherwise, though you may want to check with Mesa directly, I've never tried; but, as far as I know, as long as the amp sees a 4ohm load overall from these two jacks together, you should be fine). So this leaves a lot of options for these jacks... one 8ohm load in one jack, another 8ohm load in the other jack... which amounts to a lot of options, when you consider one of these "8ohm loads" could be two 4ohm speakers connected in series, or two 16ohm speakers in parallel; etc (and more if it is a 4-speaker setup).
Regardless... on a channel... you cannot put a load on both the 8ohm out and the paired 4ohms... you must choose one or the other: 8ohm... or 4ohm (paired).
Also... if you only use one channel; you must put the level at ZERO on the unused channel. If you are using the 2:100 as a "normal" poweramp; turn the presence knob ALL the way up (on the unused channel), and put the level at ZERO (on unused channel). But... if you are using the Recto Pre with it, and using the Pre to control the 2:100 volume, you will need to control this by NOT connecting the Recto Pre to the 2:100 on the channel you do not want to use. So; if you have the Pre's left out going to channel A, and right out going to channel B... if you only want to use channel A, then you need to disconnect the cable connecting the Pre's right out to channel B.
Hopefully this helps. Also, Google Mesa Boogie... their website has all their manuals online in PDF form.