Scando, I tried the 6072A in V2 last night for a while and really enjoyed it. Compared to the stock tube, there seemed to be less gain, less sustain, more clarity but I think the tube was only a very small part of the equation. Read on if you dare...
The rig I used to test was my '93 G&L Legacy which has been modded with a Callaham tremblock and Vintage Vibe pickups with a 5% overwind. The guitar sounds clear and chimey like a vintage STRATOCASTER. Since it was late at night, I used a pair of AKG K141 headphones with the speaker mute. My power tubes are SED Winged Cs, but I wonder how much effect that really had on the tone with headphones. No booster/compressors/overdrives before the preamp.
Basically, I found that if you look at the gain control in quadrants like four pieces of pie, you get four different characters of gain with subtle nuances within the quadrant. It started with some dry overdrive for blues or early rock'n roll and moves into some smother, juicier drive good for rock'n roll from the 70s. Pushing it past noon adds an extra layer of dirt onto the sound for single-note soloing, but you can still clean up pretty well with your volume control. Close to max gain, it sounds fuzzy but still sounded like a strat, though it wouldn't totally clean up. This is the area that would still be unusable for me, but maybe good for weaker pickups or maniacs.
Interestingly, I found the MID control has a HUGE effect on the amount of the character of the gain, just like it says in the manual. Keeping it almost all the way down open the sound up tremendously, and turning it up past noon gives the sound a nasal honk that dominates everything else. Treble and Bass have much less effect on the character of the gain. Treble just adds edge. So if you are looking for less gain, I suggested starting with the MID at the minimum and dial in from there. Of course, I played with the Contour on/off, and liked the sound a lot for solo boosts. With the gain at about noon, I found a good balance for rhythm and lead.
BTW, I was also able to find low-gain tones I liked at less than 3 o'clock with the stock tube in V2, too. So I think that the guitar you're using and the MID control has a lot to do with the amount of gain you're going to get out of this amp. I don't think the LEAD/red channel will every really do a "grainy" sounding overdrive. It's a Mesa/Boogie, and will give you that Mesa/Boogie sound that made Santana famous. For grainy crunch, stick with the Clean/green channel with the gain cranked, hot pickups, the stock tubes, and maybe a nice overdrive like an Adrock Ol'Yeller.
Incidentally, it is harder to get good crunch sounds from the Clean/green channel with a lower gain preamp tube in ANY socket from V1~4 because they're all shared by both channels. If you look at the manual, you'll know what I mean. I asked Boogie tech support whether V1 or V2 would be better for reducing the gain, but they said they hadn't tested the amp with lower gain tubes, but we should feel free to try a Boogie 12AT7 and listen. If you don't like what you hear, use a high end 5-knob pedal as a second channel.