I had the same experience when I first "discovered" Mesa amps. But after a while I learned that there is still a small percentage, maybe 10-15 percent, of sounds/tones that I hear in my head that I can't dial in on any of the amps I've owned.....and there are a few pedals that move me closer to those elusive 10% tones. So rather than do without those sounds, I did eventually go back to an OD of some sort.
What I really noticed is that having a good amp almost eliminates OD pedal GAS. I've settled on 2 or 3 that I wouldn't mind owning, but I am quite content to only own one of them at a time, and I feel little or no need to switch any time soon.
Still love me a touch of Voodoo Lab Giggity, which is supposedly more of a preamp pedal than an OD, but it's great for a quick extra bite or crunch. Still love the CmatMods stuff, especially the Butah. Love the Analogman TS9DX, and oddly the Allums modded OD3 or ODB3 is quite useful.