Well with some tweaking of the knobs, and the same cabinet, the clean channels sound all but identical, the bass stays just a touch tighter on the ED. (IMHO) The other channels it is all about setup. I think the ED does a way better rhythm/grind. The vintage lo/hi on the ED is the where it's at, love those channels. Channel 2 on the LSC can do that singing lead tone, and is amazing for crying leads and slide, the ED for rhythm and screaming leads. The LSC has not been in the house a long time either so I am still getting acquainted with both. Depending on the size venue I am at it will be stereo or mono. In the clean areas I have options/redundancy but with the settings adjusted and one with reverb and one without, the LSC going into an open 2x12 with Tone Tubby's (H-bomb) and the ED going into the closed port city with C90's I get a sweet stereo sound. I am am still wiring it all up but I am using a RJM RG-16 to do amp/channel switching. I could not give up some of my old pedals so I am using the RJM and a GCX for the pedals and the G-Major 2, all controlled by a Ground Control Pro. Some of my pedals have been with me for 15+ years and I wanted to get them off the floor, I had stopped taking some of them out and I was using clones, but it's just not the same. I am still thinking about putting EL34's in the ED, but it sounds so good now, plus I only have to carry one set of spare tubes if they are both 6l6.