Well even if they are not used in 45W mode they are still on and certainly they could effect the output.
AFA as the same not sure, but maybe
@bandit2013 knows .
Mark IIC+, III, IV, V and VII. Don't want to leave anyone out here, when running in Class A power mode (excluding the pure class A power of the V90), the Class AB tubes are cut-off completely as the cathode is disconnected from circuit ground, so no plate current will be provided by those pair of tubes. The heaters remain active, no point in turning them off, especially if you have a different power mode set for one channel. Both the V and VII have selectable power modes for each channel. Forgot about the IV if it had selectable power modes but the IIC and III did not, it was a universal choice to turn off the Class AB pair only to find out the amp sucks in the 15W power mode. Sorry for those who like that 15W of EL34 power, it is just my opinion.
However, when running in 90W mode, if one tube craps out or red-plates, it will result in overdriving the other tubes. The output power transformer is fed by a center tap of 448VDC. There are two pairs of tubes on each end of the transformer windings. In order for this thing to work it is a push-pull function as directed by the phase inverter tube. the one set is Class AB, meaning they operate in two modes, Class A when not pushed into distortion and Class B once they begin to clip resulting in cross over distortion. What many call the Class A sockets or tubes, are use much in the same manner as the Class AB tubes. They are just operating in Class AB mode but with extended Class A operation and is still a push-pull function. When one tube on one side overloads and draws excess current, the opposing side will suffer the same and will also tend to run at a higher plate current assuming you are getting any sound. The other tube next to the one that failed is not drawing any current as that is pulled from the failed tube. Sound will cut out as you basically turned the OT into a saturable reactor such that the DC current is swamping out the AC signal transfer from primary to the secondary winding. Once you hit the thermal overload in one tube, the likelihood the tubes on the opposing side are compromised as well. If for any reason the fuse fails to blow under this operating condition, the chance of damage to the OT is possible as the varnish on the windings will degrade or crack resulting in coil shorting as the OT begins to reach unbelievable temperatures so hot you cannot touch it without getting burns. Yep, that is what my Mark V90 did all the time. Still not the reason for the ice pick tones, that is related to something else. When I got my first Mark VII, and being told it sound much like the Mark V90, my thought of that nightmare came back seeing the size of the power transformer, my initial thoughts were "here we go again". So far the Mark VII has been quite reliable and not a tube amp toaster like the Mark V90 has been. Too many bad memories of the Mark V90 dread. Reason why I call the Mark V90 I have the Yule log special. It is a Christmas tradition now that I have that amp, feel cold, just fire it up and watch it fail. Yay. Sorry, I will get off of the soap box.