What everyone else said.
Last night jammed with some guys. It was a 2 guitar setup with acoustic drums.
I played in the crunch mode most of the night.
My setup was
Mark V25 head
1x12 Compact Widebody closed back cab (the one with the front port) with a Vintage 30.
I had it on a low stand facing it up. This is critical. a 1x12 facing everyone's feet won't be heard by anyone.
Playing on crunch I had the volume set to 8:30 (talking clock face here, so maybe 2 or 3 out of 10)
At one point I looked down and noticed I was actually easily keeping up in a 2 guitar setup with these settings and I was actually in 10 watt mode.
Could not believe the V25 was easily keeping up volume wise with another guitar in 10 watt mode.
Now later that night I did switch over to channel 2 for my dirt and had to put the volume up noticeably more (and switch to 25 watt mode)
When playing 2C+ mode I had the volume around 11:00, when in extreme around 9:00.
I found I really enjoyed extreme mode without the EQ then just used the EQ as my solo boost.
DISCLAIMER ON THE NEXT PARAGRAPH. I COULD BE WRONG, THIS IS JUST WHAT IT LOOKS LIKE TO ME.
I just recently started looking at different preamp designs for some older amps and what it looks to me on these (non mesa) amps is that when they add the extra clipping, you are doing exactly that, clipping the input signal. Which also clips it's amplitude. So the same "volume" setting you would have sent to the power amp before now needs to be turned up to get the same volume you would have gotten out of the non clipped signal.