I play my dual recto on a 4x12 traditional cab and I love it. I took me a while tough to find my perfect sound (including buying three cabs in the last two years). Here are my settings:
Fx loop bypassed, Bold, Silicone Diode, Sovtek 5881 powertubes and all Mesa branded preamp tubes.
Channel 2 Vintage
Presence 12:30 / Master 10:30 / Gain 12:30
Bass 11:30 / Mid 12:00 / Treble 11:00
Channel 3 Modern
Presence None / Master 9:00 / Gain 12:30
Bass 11:00 / Mids 12:30 /Treble None
Hope this helps
And a good advice: don't listen to what others say about "good" settings for a "good" tone. Tone is VERY subjective. Turn your amp ON, grab your favourite guitar, play, experiment and turn the knobs
I literally HATED channel 3 for its fizzy/metallic character, but now I use it as much as channel 2. Oh and by the way, these are rehearsal / live settings.
Cheers,
Tom.