You don't need to pull any tubes on a 60/100 MkII, just throw the switch. I have run my Simul MkII with only the outer pair installed, in the Class-A switch position. This was for a short period while testing preamp tubes, though. The manual suggests when running a 60/100 in 60 watt mode, to switch to the 4 ohm jack with an 8 ohm speaker load.