I have to agree with Inearthed....once you get to know the amp, the tweaking will subside. As far as recording, and now that I think about it, Live too...I usually adjust the position of the mic for front of house mix or for cutting a track. As some might have read in an earlier post, I use the Senheiser e609 mic for my rig. It is a fantastic mic, especially for, but not just for live sound, regardless of the price.
Some persons newer to micing a guitar rig may be surprised just how many tonal "tweaks" can be accomplished by just moving your microphone around the cabinet, or closer or farther away....
Hell, just tweak until it sounds good to you...then rawk owt, dooood.
RB