Yep, the Saturation mod does a nice job for CH3. Actually, the Mark IIC mode sound more accurate.
However, it does not address the other two channels since that gain circuit is not used in CH1 or CH2.
JAN 5751 in V1 will curb some of the early clip on all channels. I would not bother with a current production 5751 but the NOS 5751 will be more ideal. I have also tried that in V4 along with many other preamp tubes. The JAN Phillips 12AT7 does a great job in V4. It aids on reduction of the higher frequencies and yet retains the gain characteristics of the lower frequencies.
In that thread I went too far, even started modifying the amp. That is not necessary unless you have an ice pick generator like my V was. I could not use CH3 due to the ice pick issue (had to dial out presence and treble all the way) but the Saturation mod really works. It also gives you more range in the gain control due to the lower gain characteristic of the 12AT7. You will also hear a slight change in the reverb since the other half of V4 is used as a driver for the tank.
If you want to reduce the gain characteristic of CH2, V2 is one option. Some long plate 12AX7 tubes will have a lower gain character than the short plate version. JJ ECC803S is one example. It has been such a long time since I used the Mark V, forgot how it sounds. I have some other 12AT7 tubes I should try out and see what happens. I bought a NOS Mullard 12AT7 for the bass amp but did not like it. Tried it in the TC FX loop, it was ok, a bit darker in tone. The JAN Phillips 12AT7 so far has the best sound in many of the other amps that use a 12AT7 tube. Tempted to fire up the V and see what else can be done with it.
One thing to note: The Mark V does respond quite well with preamp tubes. It is one of the most tunable amps I own. I should probably pull the chassis out as I found the power tubes to feel a bit oily or wet. Not sure what was up with that but fear I may have a leaking power cap. Don't want to feed it any juice until I can confirm what may be electrolyte was just moisture due to environment.