I have an old(ish) recto 4x10 (sadly discontinued i think)with jensen speakers which i love to use in the house for clean stuff or bluesy/fusiony lead type stuff.It was my plan when i bought it to take that and my mesa 2x12 to gigs to hook up to my trusty old mark 2 and 3 heads that i play live.There,s no doubt it would sound cool the 2x12,s for bottom end thunk and the 4x10 for more high end definition and spread of sound but apart from needing a removal van every time i did a gig and getting bigger venues to play in i think it was a mesa boogie pipe dream lol.The 2x12,s do more than an adequate job anyways and i actually prefer using them to 4x12,s as well as they still have enough bottom end to rock but sound better when playing cleaner stuff.