Congratulations on the 5150!
Dunno what you mean by 'dry' exactly, but no matter, I think you'll like what a tube screamer does in front of that amp. Of course with so many variables ( guitar, pickups, amp channel, cab/speakers, music style etc...! ) I don't want to sound arbitrary, so I'll pass on my settings and you can tweak to taste...I'm making an assumption that you didn't buy a 5150 to play bluegrass, so here's my metal settings.
settings are clock...red (lead ) channel
pre 11 o'clock (ish...! )
bass 2 o'clock
middle 11-11:30
treble 11
post 9:30-10 o'clock (!)
Res 2 o'clock
Pres 9 o'clock (yup)
TS ( or sd-1, OD808 etc ) Level set for unity ( about noon ), tone 10 o'clock, gain off ( 8 o'clock )
Like so many guys I use the screamer to tighten up the bottom, punch the mids and it seems to act as a low and high pass filter/compressor/good thing. And lets not forget the other channel can sound wicked good too...crunch and bright IN, pre 2 o'clock, bass 1 o'clock, mids 9 o'clock, treble 1 o'clock, post 10 o'clock, Res 2 o'clock, Pres 4-4:30 o'clock, TS level noonish, tone 10-11 o'clock, gain 9 o'clock.
I never turn off my OD...sorry for the long post, hope it works out for you .