I like things simple and only change Vol1, Vol2 and Mid. I tend to leave Treble on 6-7, Bass on 4, Presence on 2, Rev on 4, Master on 2-3, 60w setting, tweed mode. Plenty loud enough!
With the strat, and using the gtr volume control to go from clean to crunch, Vol1 on 5, Vol2 on 2, Mid on 3...