The GT10 can do many, many things- but can really only "switch" one thing via the 1/4" out (amp channel switch).
I love the GTs as all-in-one solutions, but it is only fully realized if you have a 2 channel amp.
Using one with the V would "create" some issues as you would not be able to retire the V footswitch. The 10 does have up to 4 EQs available per patch though, so you could match the amp EQ to a GT EQ then switch those around as needed. GTs are powerful, and are really only limited by *you*....I have been through the 6, 8, and 10, and only recently (8 months ago) decided to go "all-out" and build my dream board. The GTs are not in the same league in sound quality, but they are more "foot friendly" when set up right.