Just one mans opinion... don't have a Fillmore but have played with a Jan 12at7 in a few Mesas. With less overall gain the difference with the at7 is not huge but noticeable. In my IIC+ HR the at7 in the V5 PI cleaned up Ch 1 and provided better lower end clarity with lower Vol 1 settings, which is what I was looking for. In my V:90 V7 the lower gain was evident as the output volume was lower with the same settings, but there was no noticeable tone difference so have since reverted back to the 12ax7.
The choice really depends on what one is looking for, with the PI it can't hurt to try it out.. it may end up being meh or you could end up liking it 8)